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The Weirdest Thing I Learned This Week hits Apple, Spotify, YouTube, and everywhere else you listen to podcasts every-other Wednesday morning. It’s your new favorite source for the strangest science-adjacent facts, figures, and Wikipedia spirals the editors of Popular Science can muster. If you like the stories in this post, we guarantee you’ll love the show.

FACT: Marie Antoinette probably had braces

By Rachel Feltman

The idea of Marie Antoinette in orthodontic braces probably sounds like something out of my favorite Sofia Coppola film, but it’s not as anachronistic as it sounds. While I couldn’t find a definitive primary source on the subject, there are historical mentions of Marie Antoinette undergoing orthodontic treatment. And in some ways, it would be more surprising if she didn’t do a stint in braces: modern dentistry as we know it was essentially invented in France in the early 1700s, and by the time Marie and Louis got hitched, French people were practically known for having straight, pretty teeth. We know that Marie Antoinette was given an intense French makeover in all things before being shipped off to Versailles, so it’s plausible that she had a bit of dental work done, too. 

If the idea of 18th century orthodontia makes you want to put your head between your knees, you’re not wrong. The hardware designed by Pierre Fauchard, called a bandolet or bandeau, used a horseshoe-shaped piece of metal that pressed against the inside or outside of the dental arch. Dentists would manually tie individual teeth to the appliance using either silk threads or thin metal wires. That is, admittedly, pretty identical to how braces work today—they exert constant pressure on teeth to help move them into new positions, then hold them there while everything settles into place. But modern braces are designed to move teeth more effectively and with as little pain as possible, and the bandeau was much more of a blunt instrument. 

For a fun French dental bonus fact, I dug into the weird social history of smiling on the eve of the Revolution. Check out this week’s episode to learn more! 

FACT: One woman’s cells have fueled most medical research for decades 

Featuring Hari Kondabolu and Dr. Priyanka Wali

Today’s special guests are comedian Hari Kondabolu and physician-slash-comedian Priyanka Wali. Together they host the podcast Health Stuff, where they dive into everything from earwax to sleep hygiene.

On this week’s episode of Weirdest Thing, Hari and Priyanka share the story of Henrietta Lacks. While being treated for cervical cancer at Johns Hopkins in the 1950s, this African American mother of five unknowingly—and involuntarily—changed the course of medical history. Cancer cells from one of her biopsies were sent off for research without her knowledge or consent. Unlike other cancer cells in the lab, hers kept doubling instead of dying off. They were the first human cells that were discovered to multiply easily in a lab setting, making them perfect for studying the impact of various drugs, hormones, viruses, and toxins. While the cell line that originates from Henrietta Lacks’ tissues—called the HeLa line—has been used in research that’s saved countless lives over the decades, they also serve as a reminder of the entrenched racism of our medical system.

Listen to this week’s episode to learn more about Henrietta’s story. And for a deeper dive, check out “The Immortal Life of Henrietta Lacks.” 

FACT: It’s possible that neanderthals knew how to treat cavities 

By Rachel Feltman

Surprise, more teeth! Scientists recently reported that a 59,000-year-old tooth—a neanderthal molar, to be precise—could conceivably have been drilled to treat a cavity. They came to that conclusion by tinkering with three modern teeth, AKA subjecting them to the horrors of prehistoric dental treatment, to show that the ancient chomper showed signs of the same. 

Unsurprisingly, not everyone is 100 percent convinced by the experimental evidence. But even if hominids weren’t drilling cavities that long ago, there’s good reason to believe we’ve been at it for longer than you might guess. A couple of teeth from the Stone Age (about 13,000 years ago) show less ambiguous signs of dental drilling, and dentistry has been a flourishing (if often misguided) practice for thousands of years. Many of our ancient ancestors even wore dental bridges made out of gold and other precious metals—so grills have a long, proud history.