Psilocybin use has surged in the United States since 2019
The use of psilocybin—the active compound in so-called “magic mushrooms”—has increased significantly in the United States since 2019, according to a new study published in the Annals of Internal Medicine. Drawing on data from five national sources, researchers found sharp increases in both lifetime and recent use, especially among adults with symptoms of anxiety, depression, and chronic pain. Psilocybin is a naturally occurring hallucinogen found in certain species of mushrooms. It has attracted growing scientific and public attention due to promising early studies suggesting it may help treat depression, post-traumatic stress disorder, and substance use disorders. Although not currently approved by the U.S. Food and Drug Administration, psilocybin has entered clinical trials and has been decriminalized or legalized in parts of Oregon, Colorado, and several municipalities. This shifting legal landscape has raised questions about whether broader public use is increasing—and what the public health consequences might be. “With efforts to legalize psilocybin mushrooms in Colorado, Oregon, and elsewhere ongoing, we wanted to determine whether there were more people using psilocybin mushrooms now than when legalization …