All posts tagged: patient

Patient Leaves Hospital as Transplanted Gene-Hacked Pig Organ Seems to Be Functioning Well

Patient Leaves Hospital as Transplanted Gene-Hacked Pig Organ Seems to Be Functioning Well

Image by Mass General Hospital/Michelle Rose Last month, surgeons at the Massachusetts General Hospital in Boston transplanted a kidney from a gene-hacked pig into a living 62-year-old man. The unusual procedure appears to have been a resounding success, with the patient being discharged from the hospital on Wednesday. The achievement could usher in a new era, potentially reducing our reliance on both hard-to-come-by human donor kidneys and the expensive dialysis machines that treat kidney disease and failure. The patient, Richard Slayman, had been struggling with kidney disease for over a decade. His previously transplanted human kidney had also shown signs of failure last year. But with his new kidney, which came from a genetically modified pig courtesy of biotech company eGenesis, Slayman is already doing much better. The organ is producing urine and removing waste from the blood, among other key functions, as the New York Times reports. “This moment — leaving the hospital today with one of the cleanest bills of health I’ve had in a long time — is one I wished would come …

Pig kidney transplant patient leaves Massachusetts hospital | US News

Pig kidney transplant patient leaves Massachusetts hospital | US News

The first patient to receive a kidney transplanted from a genetically modified pig has been discharged from hospital. Richard “Rick” Slayman received the organ in March in a world first after undergoing a four-hour surgery at the Massachusetts General Hospital (MGH) in Boston. The 62-year-old suffers from end-stage renal failure, a chronic disease where the kidneys can no longer function on their own. “This moment – leaving the hospital today with one of the cleanest bills of health I’ve had in a long time – is one I wished would come for many years,” he said in a statement on Wednesday. “Now, it’s a reality and one of the happiest moments of my life.” Image: Mr Slayman thanked well-wishers. Pic: Michelle Rose/Massachusetts General Hospital He thanked all the medical staff involved and who have cared for him – before and after – his “historic transplant”. He added: “I’m excited to resume spending time with my family, friends, and loved ones free from the burden of dialysis that has affected my quality of life for many …

Gene Editing Experiment Halted as Patient Gets Weird Side Effects

Gene Editing Experiment Halted as Patient Gets Weird Side Effects

Image by Getty / Futurism The experimental biotech startup Verve Therapeutics has paused the first phase of a buzzy human gene-editing trial due to strange side effects in a patient, according to a report from Bloomberg. The trial in question — dubbed the “Heart-1” trial — is the company’s attempt to use gene editing to reduce heart-attack-causing cholesterol in patients with familial hypercholesterolemia, a passed-down genetic disorder that causes buildups of LDL cholesterol in individuals. LDL is the bad kind of cholesterol, and familial hypercholesterolemia drastically heightens patients’ risk of early heart attack and can lower life expectancy overall. Verve’s proposed solution: inject “VERVE-101,” a serum designed to lower fatty LDL molecules by genetically altering the cholesterol-managing PCSK9 gene, into trial participants’ livers. While promising tests on monkeys paved the way for Verve’s much-anticipated human trial, however, Heart-1 has now hit another speed bump. Late last year, it was revealed that a patient enrolled in Heart-1 had passed away from a heart attack. A panel of experts concurred that VERVE-101 wasn’t responsible — according to Nature, …

Sun Ra Plays a Music Therapy Gig at a Psychiatric Hospital & Inspires a Patient to Talk for the First Time in Years

Sun Ra Plays a Music Therapy Gig at a Psychiatric Hospital & Inspires a Patient to Talk for the First Time in Years

For some time now it has been fash­ion­able to diag­nose dead famous peo­ple with men­tal ill­ness­es we nev­er knew they had when they were alive. These post­mortem clin­i­cal inter­ven­tions can seem accu­rate or far-fetched, and most­ly harmless—unless we let them col­or our appre­ci­a­tion of an artist’s work, or neg­a­tive­ly influ­ence the way we treat eccen­tric liv­ing per­son­al­i­ties. Over­all, I tend to think the state of a cre­ative individual’s men­tal health is a top­ic best left between patient and doc­tor. In the case of one Her­man Poole Blount, aka Sun Ra—com­pos­er, band­leader of free jazz ensem­ble the Arkestra, and “embod­i­ment of Afro­fu­tur­ism”—one finds it tempt­ing to spec­u­late about pos­si­ble diag­noses, of schiz­o­phre­nia or bipo­lar dis­or­der, for exam­ple. Plen­ty of peo­ple have done so. This makes sense, giv­en Blount’s claims to have vis­it­ed oth­er plan­ets through astral pro­jec­tion and to him­self be an alien from anoth­er dimen­sion. But ascrib­ing Sun Ra’s enlight­en­ing, enliven­ing mytho-theo-phi­los­o­phy to ill­ness or dys­func­tion tru­ly does his bril­liant mind a dis­ser­vice, and clouds our appre­ci­a­tion for his com­plete­ly orig­i­nal body of work. In fact, Sun Ra him­self discovered—fairly ear­ly …

Scientists Inject Patient With Slurry to Make Them Grow a New Liver

Scientists Inject Patient With Slurry to Make Them Grow a New Liver

Image by Getty / Futurism An experimental new medical treatment to grow a liver inside someone’s body has just hit a major milestone. After a decade of development, the biotech company LyGenesis has announced that for the first time, a human patient has been dosed with a cocktail of donated liver cells to — hopefully — transform one of their lymph nodes into a small but functioning liver. The cell therapy injection was performed on March 25, Wired reports, in a Phase 2a clinical trial that will see 12 adults with end-stage liver disease (ESLD) receive the treatment. Each year, about 4.5 million adults in the US are diagnosed with liver disease and over 50,000 die from it, according to the Centers for Disease Control and Prevention. By growing even just a little amount of liver mass, the treatment could provide significant relief to severely ill patients who can’t receive a transplant. “We’re using the lymph node as a living bioreactor,” Michael Hufford, cofounder and CEO of LyGenesis, told Wired. Livers, like pretty much any …

HHS tells hospitals to get patient consent before invasive exams

HHS tells hospitals to get patient consent before invasive exams

Hospitals must obtain informed consent from patients before allowing physicians to conduct sensitive and invasive examinations such as pelvic and prostate, particularly if the patients are under anesthesia, the Department of Health and Human Services (HHS) said Monday.  In new guidance and in a letter sent to teaching hospitals, HHS Secretary Xavier Becerra and other officials said they were acting based on “increasing concerns” about the absence of informed patient consent in educational settings.   “The Department is aware of media reports as well as medical and scientific literature highlighting instances where, as part of medical students’ courses of study and training, patients have been subjected to sensitive and intimate examinations,” HHS said in the letter.  “It is critically important that hospitals set clear guidelines to ensure providers and trainees performing these examinations first obtain and document informed consent from patients before performing sensitive examinations in all circumstances,” the agency said.  A New York Times investigation in 2020 found that hospitals and physicians, including medical students in training, aren’t required to obtain explicit consent from …

First N1 Neuralink patient talks about installation and benefits

First N1 Neuralink patient talks about installation and benefits

In an unprecedented medical breakthrough, the first N1 Neuralink patient, Nolan, has stepped forward to share his transformative experience. Living with paralysis, Nolan’s life has been revolutionarily enhanced by this state-of-the-art Brain-Computer Interface (BCI) technology, which has bestowed upon him a level of independence that was previously unattainable. This groundbreaking technology has the potential to change the lives of countless individuals living with paralysis, offering them a renewed sense of hope and possibility. The Neuralink Implantation Process At the forefront of this narrative is the remarkable ease and efficiency of the implantation surgery, which Nolan underwent. Contrary to his initial apprehensions, the procedure was completed swiftly, and his recovery was notably quick, suggesting a future where such technology could not only restore function but also expedite healing after injury. The minimally invasive nature of the surgery and the rapid recovery time demonstrate the advancements made in the field of neurotechnology, paving the way for more accessible and less daunting treatments for paralysis. Neuralink N1 Features The N1 Implant is hermetically sealed in a biocompatible enclosure …

From the archive: ‘Is anybody in there?’ Life on the inside as a locked-in patient – podcast | News

From the archive: ‘Is anybody in there?’ Life on the inside as a locked-in patient – podcast | News

We are raiding the Guardian Long Read archives to bring you some classic pieces from years past, with new introductions from the authors. This week, from 2020: Jake Haendel spent months trapped in his body, silent and unmoving but fully conscious. Most people never emerge from ‘locked-in syndrome’, but as a doctor told him, everything about his case is bizarre. By Josh Wilbur How to listen to podcasts: everything you need to know Source link

Neuralink Told Its First Human Patient Not to Worry About Those Gruesome Monkey Deaths

Neuralink Told Its First Human Patient Not to Worry About Those Gruesome Monkey Deaths

Image by Getty / Futurism The first patient to get a Neuralink implant had questions about the company before allowing it to cut into his skull — but his concerns, apparently, were quelled. “I read a lot of the negative stuff about this before the surgery — about all the terrible things that [the company was] putting the monkeys through and how awful it was, monkeys like picking out their implant and rubbing it on the ground and all sorts of stuff,” Noland Arbaugh, Neuralink’s first patient, said during an all-hands meeting at the company that he later posted to X-formerly-Twitter. After speaking with “the monkey people” at the company, however, Arbaugh says his concerns were put to rest. “I realized how just wrong all that is,” said the 29-year-old, who has for eight years suffered from quadriplegia, or near-complete paralysis, stemming from a diving accident. What Arbaugh was referring to, it seems, are all the reports about the horrific outcomes for the rhesus macaques Neuralink used to test its brain-computer interface (BCI) chips. It’s unclear …

Neuralink’s First Patient Heard About Brain Implant in Drunk-Dial From Friend

Neuralink’s First Patient Heard About Brain Implant in Drunk-Dial From Friend

Image by Neuralink / Futurism Overnight celebrity Noland Arbaugh, the first person to get a Neuralink brain-computer interface (BCI) implanted, learned about the Elon Musk-owned company’s human trials in chaotic fashion. In an interview with the Wall Street Journal, the 29-year-old — who became paralyzed after a diving accident eight years ago — said he only learned about Neuralink six months ago, thanks to a drunk phone call from a friend. That friend called him up while under the influence to tell him that Neuralink was looking for its first human trial patient. He helped Arbaugh fill out the application, but apparently misspelled his name in the process. It’s an unsurprising anecdote from the Arizona-based young man, who per Neuralink engineer Bliss Chapman, said his favorite game was “Beerio Cart,” a clearly alcohol-tinged variant on the party game Mario Kart that Arbaugh was seen playing with his mind in an impressive demo posted last week. “They’re very different games,” the 29-year-old games enthusiast quipped. For all his seeming frat boy antics, Arbaugh does seem — as Neuralink …