Brain region identified as key controller of aggression
Scientists have discovered that a specific area within the brain, known as the cortical amygdala, plays a pivotal role in determining whether male mice behave aggressively or in a friendly manner. This region becomes active when male mice detect scents from other males and when they engage in aggressive actions. Researchers found that reducing the activity of this brain area lessened aggressive behaviors and encouraged more sociable interactions. This work, published in Nature, is the first to pinpoint a single brain area capable of halting aggressive social behavior and encouraging pro-social actions. Researchers at Mount Sinai were interested in this topic because aggression is a fundamental behavior across species, and studying it in detail could reveal general principles about how the brain controls behavior. “Aggression is a highly conserved behavior of great importance throughout the animal kingdom, explained study author Antonio Aubry, an instructor at the Icahn School of Medicine. “Thus, by studying the neurobiology of aggression, it has the potential to uncover general principles regarding the relationship between the brain and behavior across a …