All posts tagged: Artery

Researchers uncover inflammatory pathways connecting depression and coronary artery disease

Researchers uncover inflammatory pathways connecting depression and coronary artery disease

In a new study published in Nature Mental Health, researchers from Vanderbilt University Medical Center and Massachusetts General Hospital have discovered potential genetic links between coronary artery disease, major depression, and cardiomyopathy — a condition that affects the heart muscle. The findings suggest that these links are mediated by inflammatory pathways and that medications used for coronary artery disease and depression might, together, help reduce inflammation and the risk of developing cardiomyopathy. Coronary artery disease is one of the most common types of heart disease and a leading cause of death worldwide. It occurs when the major blood vessels that supply the heart with blood, oxygen, and nutrients (coronary arteries) become damaged or diseased. Cholesterol-containing deposits (plaques) in the arteries and inflammation are usually to blame. As these plaques build up, they narrow the arteries, decreasing blood flow to the heart. This can result in chest pain, shortness of breath, or other symptoms, and can lead to more serious complications like heart attacks. Major depression, also known as major depressive disorder (MDD), is a serious …

Anorexia Nervosa and Superior Mesenteric Artery Syndrome

Anorexia Nervosa and Superior Mesenteric Artery Syndrome

Source: outsideclick/Pixabay Anorexia nervosa (AN) is an eating disorder with signs and symptoms of severe weight loss, restrictive eating, and fear of weight gain. While not everyone with AN is severely underweight, many individuals with this disorder experience drastic weight loss. Severe weight loss in AN is dangerous because it can lead to additional health complications, such as Superior Mesenteric Artery Syndrome (SMAS), which can hinder AN recovery. Superior Mesenteric Artery Syndrome (SMAS) SMAS is a condition where substantial weight loss causes the fat pad surrounding the superior mesenteric artery (SMA) in the digestive tract to shrink.1,2,3 This fat pad is an important part of the body because it holds the SMA in place away from the small intestine. When this fat pad shrinks, the SMA moves and the small intestine becomes squeezed between it and the aorta (i.e., main blood vessel of the body). This squeezing narrows the small intestine and prevents food in the stomach from entering it. This intestinal blockage causes great abdominal discomfort for individuals with SMAS during and after eating. …